Best Bets for NCAA Basketball Picks Against the Spread for Wednesday, February 26

Published 3:22 am Wednesday, February 26, 2025

Wednesday’s college basketball schedule has several interesting games, including the matchup between the Georgetown Hoyas and the UConn Huskies, and you’ll find our best bets against the spread for 10 games here.

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Today’s NCAA Men’s Basketball Picks ATS

ATS Pick: Georgetown +12.5 vs. UConn

  • Matchup: Georgetown Hoyas at UConn Huskies
  • Time: 6:30 p.m. ET
  • Date: February 26
  • Computer Projection: UConn by 6.4 points (Bet now on BetMGM)
  • Spread: UConn (-12.5)
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: SMU -2.5 vs. Cal

  • Matchup: SMU Mustangs at California Golden Bears
  • Time: 11 p.m. ET
  • Date: February 26
  • Computer Projection: SMU by 6.6 points (Bet now on BetMGM)
  • Spread: SMU (-2.5)
  • TV Channel: ESPNU
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Memphis -13.5 vs. Rice

  • Matchup: Rice Owls at Memphis Tigers
  • Time: 8 p.m. ET
  • Date: February 26
  • Computer Projection: Memphis by 16.6 points (Bet now on BetMGM)
  • Spread: Memphis (-13.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: East Tennessee State -9.5 vs. Mercer

  • Matchup: Mercer Bears at East Tennessee State Buccaneers
  • Time: 6 p.m. ET
  • Date: February 26
  • Computer Projection: East Tennessee State by 12.6 points (Bet now on BetMGM)
  • Spread: East Tennessee State (-9.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Lipscomb -19.5 vs. Central Arkansas

  • Matchup: Central Arkansas Bears at Lipscomb Bisons
  • Time: 8 p.m. ET
  • Date: February 26
  • Computer Projection: Lipscomb by 22.2 points (Bet now on BetMGM)
  • Spread: Lipscomb (-19.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

Bet on this or any men’s college basketball matchup at BetMGM.

ATS Pick: Holy Cross +9.5 vs. Colgate

  • Matchup: Holy Cross Crusaders at Colgate Raiders
  • Time: 7 p.m. ET
  • Date: February 26
  • Computer Projection: Colgate by 6.8 points (Bet now on BetMGM)
  • Spread: Colgate (-9.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Utah +14.5 vs. Arizona

  • Matchup: Utah Utes at Arizona Wildcats
  • Time: 9 p.m. ET
  • Date: February 26
  • Computer Projection: Arizona by 11.9 points (Bet now on BetMGM)
  • Spread: Arizona (-14.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Ohio State +1.5 vs. USC

  • Matchup: Ohio State Buckeyes at USC Trojans
  • Time: 10:30 p.m. ET
  • Date: February 26
  • Computer Projection: Ohio State by 1.1 points (Bet now on BetMGM)
  • Spread: USC (-1.5)
  • TV Channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Kansas State +4.5 vs. UCF

  • Matchup: Kansas State Wildcats at UCF Knights
  • Time: 7 p.m. ET
  • Date: February 26
  • Computer Projection: UCF by 1.9 points (Bet now on BetMGM)
  • Spread: UCF (-4.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: American -3.5 vs. Navy

  • Matchup: Navy Midshipmen at American Eagles
  • Time: 7 p.m. ET
  • Date: February 26
  • Computer Projection: American by 6.0 points (Bet now on BetMGM)
  • Spread: American (-3.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

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